What is low growth hormone?
Growth hormone (GH) is a protein hormone released by the pituitary gland that stimulates growth, cell reproduction, and regeneration. Low growth hormone, also called growth hormone deficiency, occurs when the pituitary gland does not produce enough GH.
Some key facts about low GH:
- Causes: Damage or tumors in the hypothalamus or pituitary gland, genetic mutations, injuries or radiation treatment affecting these areas of the brain. Often the exact cause is unknown.
- Symptoms: Children may experience slower than normal growth and short stature. Adults can have decreased muscle mass, increased body fat, fatigue, poor concentration, high cholesterol, and reduced quality of life.
- Diagnosis: Comprehensive medical history, physical exam focusing on height and growth patterns, often combined with stimulation tests that measure GH levels after ingesting substances that normally trigger GH release.
- Treatment: Daily injections of synthetic growth hormone to replace the deficient hormones. Improves height in children and reverses some symptoms in both children and adults.